中山大学学报自然科学版 ›› 2010, Vol. 49 ›› Issue (2): 148-150.

• 研究论文 • 上一篇    

折苞斑鸠菊中的黄酮类成分

王韵华1,2,王 军1,马文哲1   

  1. (1中山大学药学院,广东 广州 510006;2广东省药品检验所,广东 广州 510180)
  • 收稿日期:2009-06-15 修回日期:1900-01-01 出版日期:2010-03-25 发布日期:2010-03-25

Flavones of Vernonia spirei Gandog

WANG Yunhua1,2,WANG Jun1, MA Wenzhe1   

  1. (1School of Pharmaceutical Sciences, Sun Yatsen University, Guangzhou 510006, China;2Guangdong Institute for Drug Gontrol, Guangzhou 510180,China)
  • Received:2009-06-15 Revised:1900-01-01 Online:2010-03-25 Published:2010-03-25

摘要:

用硅胶、反相硅胶、凝胶和薄层色谱等方法从折苞斑鸠菊(Vernonia spirei Gandog)甲醇提取物的乙酸乙酯部分中分离黄酮类成分,得到2个化合物,通过光谱和波谱分析,分别鉴定为:5,7,4 ’-三羟基-6,3-二甲氧基黄酮(Ⅰ)、5,7,4 ’-三羟基-6,3-二甲氧基黄酮(Ⅱ)。以上化合物均为首次从该植物中分离得到。


关键词: 折苞斑鸠菊, 黄酮

Abstract: The chemical constituents of Vernonia spirei Gandog were studied. The constituents were separated and purified from MeOH extract of the whole plant with column chromatographic methods through silica gel, RP18 silica gel, Sephadex LH20, HPLC, and preparative TLC. Their chemical structures were characterized by spectroscopic methods including NMR and EIMS. The result showed that Vernonia spirei Gandog contained two components including 5,7,4〖DK〗’trihydroxy6,3 ’dimethoxyflavone(Ⅰ), 5,3 ’dihydroxy6,7,4 ’trimethoxyflavone(Ⅱ). These compounds were obtained from this genus for the first time.

Key words: Vernonia spirei Gandog, flavones

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