关键词: 鸡血藤, 缩合鞣质, 总黄酮, 抗肿瘤细胞增殖

Abstract: The contents of total flavonoids and condensed tannins in the ethanol extract of Spatholobus suberectus Dunn and its different solvents partitioned extracts were determined by ultraviolet spectrophotometry and VanillinH₂SO₄ method, respectively. The contents of total flavonoids in the φ=60% ethanol extract, ethyl acetate insoluble extract, ethyl acetate partitioned extract, n-butanol partitioned extract, water residue were （6.49±1.99）%，（7.36±0.13）%，（9.35±0.22）%，（8.41±0.27）%，（4.48±1.53）%， respectively, while their contents of condensed tannins were （51.09±0.37）%，（52.34±4.73）%，（73.22±2.72）%，（83.11±5.87）%，（29.74±2.12）%, respectively. The inhibitory activities on the proliferation of HT-29 and MCF-7 tumor cells were determined by MTT. The extract samples all showed inhibitory activities in different extent on the proliferation of HT-29 and MCF-7 tumor cells. The nbutanol partitioned extract had the strongest inhibitory activities on the proliferation of both tumor cells.

Key words: Spatholobus suberectus Dunn, condensed tannins, total flavonoids, anti-proliferation of tumor cell